The best Side of tilidin und novaminsulfon zusammen einnehmen
Soon after oral administration, tilidine is fast absorbed. It truly is subject matter to a pronounced to start with-pass impact. The conversion of tilidine to the more potent Energetic metabolite nortilidine takes place With all the involvement of CYP3A4 and CYP2C19. Inhibition of such enzymes may Therefore alter the efficacy and tolerability profi